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Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity:
Intended target=RSK2; SL0101 is a natural product ATP-competitive kinase inhibitor; Limited validation data are available regarding the activity of this compound against kinases. Smith et al. Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res. 65, 1027-34 (2005).