Solubility - preferred solvent:
DMSO or ethanol
Solubility - concentration:
100 mM
NMR:
1H NMR (400 MHz, methanol-d4) d 8.07 (s, 1H), 7.44 (s, 1H), 7.24 (d, J = 8.8 Hz, 2H), 7.18 (d, J = 8.8 Hz, 2H), 6.14 (d, J = 4.8 Hz, 1H), 4.44 (dd, J = 5.1, 5.1 Hz, 1H), 4.17 (dd, J = 5.3, 5.3 Hz, 1H), 4.09 (ddd, 5.0, 5.0, 6.5 Hz, 1H), 3.28-3.16 (m, 2H), 3.06 (ap quin, J = 6.5 Hz, 1H), 2.84 (dd, J = 3.9, 13.8Hz, 1H), 2.71 (dd, J = 6.8, 13.8 Hz, 1H), 2.60 (t, J = 6.6 Hz, 2H), 1.68 (quin, J = 6.8 Hz, 2H), 1.28 (s, 9H), 1.04 (d, J = 6.5 Hz, 3H), 1.02 (d, J = 6.5 Hz, 3H);
13C NMR (100 MHz, methanol-d4) d 158.74, 158.66, 153.5, 151.0, 146.6, 138.2, 126.6, 123.3, 120.5, 103.4, 89.8, 89.3, 84.3, 75.4, 73.6, 53.9, 52.1, 39.7, 35.1, 32.0, 29.3, 18.4, 18.0 (one signal missing);
Chemical Probes Portal SGC0946.pdf
