ONC201

Compound status: 
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity: 

Intended target=Induction of TRAIL pathway (PMID: 23390247); subsequent publications indicate ONC201's antitumor activity is due to TRAIL-dependent and -independent mechanisms, including the induction of a cellular stress response (PMIDs: 26884599, 26884600, 28423492, 28424227, 28700333).

Probe Availability

Probe Information