NS-018

Compound status: 
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity: 

Broad specificity kinase inhibitor: Intended target JAK2; Inhibits JAK2 and SRC family kinases. Reference Nakaya et al., 2011, Efficacy of NS-018, a potent and selective JAK2/Src inhibitor, in primary cells and mouse models of myeloproliferative neoplasms. Blood Cancer J. 1, e79.

Probe Information