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Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity:
Broad specificity BCL2 protein inhibitor: Intended target=BCL2; This is a high quality compound that inhibits multiple BCL2 proteins. Tse et al., ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor. Cancer Res 68, 3421-8 (2008).