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Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity:
Intended target: CREBBP-p53 protein-protein interaction; this is a fragment with very weak potency for the target. It is not potent enough for application as a chemical probe in cells. Sachchidanand et al., Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 13, 81-90 (2006).