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Matthew Robers is a Senior Research Scientist and Group Leader at Promega Corporation. Prior to joining Promega, Matt was focused on pathway analysis in the cell-based assay group at Life Technologies. Matt has authored numerous peer-reviewed publications and published patents on the application of novel fluorescent and bioluminescent chemistries to measure intracellular protein dynamics. The focus of Matt’s team at Promega is to apply new technologies to assess target engagement, and this team has recently developed a biophysical technique for quantifying compound affinity and residence time at selected intracellular targets within intact cells.