This page will be expanded over time to include more references, but we begin by recommending a small number of outstanding, important papers that cover topics that should be of broad interest to scientists who use chemical probes.
- The promise and peril of chemical probes by Arrowsmith et al. (Nature Chemical Biology)
- The Art of the Chemical Probe by Stephen V Frye (Nature Chemical Biology)
- Probing the probes: fitness factors for small molecule tools by Paul Workman & Ian Collins (Chemistry & Biology)
- Target validation using chemical probes by Mark E Bunnage, Eugene L Piatnitski & Lynn Jones (Nature Chemical Biology)
- Data gaps that limit the potential of preclinical research by Robin J Kleiman & Michael D Ehlers (Science Translational Medicine)
- Applications of chemogenomic library screening in drug discovery by Lynn Jones & Mark Bunnage (Nature Reviews Drug Discovery)
- Developing predictive assays: the phenotypic screening "rule of 3" by Fabien Vincent et al. (Science Translational Medicine)
- Choose and use your chemical probe wisely to explore cancer biology by Julian Blagg & Paul Workman (Cancer Cell)
- Public resources for chemical probes: the journey so far and the road ahead by Albert Antolin et al. (Future Medicinal Chemistry)
- Discovering and validationg cancer genetic dependencies: approaches and pitfalls by Ann Lin & Jason M. Shelttzer (Nature Review Genetics)
- Systematic Chemogenetic Library Assembly by Stephen M Canham et al. (Cell Chemical Biology)
