K00564a

Compound status: 
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity: 

According to Anastassiadis T et al Nat. Biotechnol., 29 (11): 1039-45. [PMID:22037377] K00564a has a broad spectrum of inhibition. Screened against a panel of 300 Kinases, it shows 22 hits including TRKA/B/C, RSK3/4, RET, MLK3, LRKK2, IRAK4, FLT3, CHK2 which % inhibition is far greater than SYK (Intended target).

Probe Information