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Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity:
This compound was initially reported as an inhibitor of SAH hydrolase and has been routinely applied at excessive concentrations as a catalytic EZH2 inhibitor. Arrowsmith et al., The promise and peril of chemical probes. Nat. Chem. Biol. 11, 536-41 (2015).