C646
Compound status:
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.Note about activity:
Cys reactive compound: Intended targets=E1A binding protein p300, CREB binding protein; Reacts with Cys-rich proteins including tubulins and inhibits tubulin polymerization; Shrimp et al., Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300. ACS Med Chem Lett. 7, 151-5 (2015).
