Compound status: 
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity: 

Intended target=Keap1-Nrf2 antioxidant response pathway; found to be a global protein synthesis inhibitor; Vartanian et al., Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis. Mol. Cell. Proteomics 15, 1220-31 (2015).

Probe Information