Bromosporine

Compound status: 
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity: 

pan-Bromodomain inhibitor; Bromosporine was designed as a promiscuous panBromodomain inhibitor; Picaud et al., Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv. 2, e1600760 (2016).

Probe Information