Adenosine dialdehyde

Compound status: 
Historic compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Note about activity: 

Intended target=protein methyltransferase; this compound results in SAH accumulation, which feeds back to inhibit SAM-dependent methylation but this mechanism is not specific enough to study specific methyltransferases. Shortt, J., et al., A chemical probe toolbox for dissecting the cancer epigenome. Nat Rev Cancer. 17, 160-183 (2017).

Probe Information